Gaming: Resident Evil Requiem's The Final Puzzle May Be The Most Convoluted...
Take three steps to the left when you hear the bird sing twice after midday.
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Throughout my playthrough of Resident Evil Requiem, I came across a few items which I had absolutely no clue what to do with. I investigated some further, but didn't dwell on it; I had a review to write after all. But after getting to the end, a checkbox for The Final Puzzle popped up in the challenges menu. Great, now I'm even more confused.
After endless discussions with PC Gamer's senior guides writer Sean Martin and a helpful peep at IGN's The Final Puzzle reveal, we've finally gotten to the bottom of what all these extra items were for. Well, most of them.
Spoiler warning for Resident Evil Requiem puzzle solutions and story elements ahead
It's just as convoluted as we feared. Towards the end of Rhodes Hill Hospital, you'll find a weird and gory item called the Severed Hand. Ok. What does this do? Well, if you put it under one of the laser microscopes you can find around Rhodes Hill, it'll reveal the following: GGC AAG AUA UGU CAU, along with this message: "Let's play." No, I don't think I will.
The string of letters is actually a DNA sequence. You get to keep the hand even after you've analysed it, so I just thought it was an easter egg at first. Resident Evil deals with a lot of infectious viruses and mutations, after all. But no, it's actually the start of something way bigger than I could've imagined.
There are several stages you need to complete throughout the course of the rest of Resident Evil Requiem, which'll then land you with the prize of ticking off The Final Puzzle checklist. But here's the kicker: no one seems to have been able to solve this puzzle yet, including us.
The trick seems to be finding out which of the following symbols: Moon, Star, and Sun, correspond to the letters in the DNA sequence. I spent about five minutes turning an hourglass around in Grace's hands while in Gideon's secret lab, before shoving it back in my inventory, never to be used again. But now I discover it has a secret code written into its base, which you can only see if you hold it upside down and wait for the sand to fall away.
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Source: PC Gamer